I have the same problem. I use AVG Antivirus, and if I disable the AVG Antivirus (NOT RECOMMENDED), GTAV and Rage startup and then I can run LSPDFR without issues.
Note: Disabling Antivirus is not recommended. To clarify, I turn mine off, and once LSPDFR is loaded, I re-enable my AVG Antivirus, but am exposed while it is off.
There is a way, which I have not yet figured out, to customize AVG to allow Rage and LSPDFR to load without disabling the AVG Antivirus, but I have not figured that out. If anyone knows how to do that, please let us know.