Kyben, Anderson and Darkmyre thanks for your help much appreciated. I uninstalled GTA today and reinstalled it. I reinstalled all of the mods and plugins that I use for LSPDFR and most of them seem to run fine without game crashing so It could of been a corrupt meta file.
However I do get the random crash either at the beginning or 30 mins into playing so it could also be one of the issues Anderson stated. I can see now why you use 46 and not 47 Darkmyre lol. I never had that many issues then I did before update.