Alright, well since the description is already done - the log details the problem in it's whole - so...
Also, I am using many mods but I'll give you the contents of the error in the log ScriptHookDotNet.
Log:
2014-09-22 17:45:20 - Error during Tick in script 'LCPDFR_Loader.Loader':
System.IO.IOException: The process cannot access the file 'C:Program Files (x86)Rockstar GamesEFLCLCPD First Response.dll' because it is being used by another process.
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy, Boolean useLongPath, Boolean checkHost)
at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access, FileShare share)
at LCPDFR_Loader.Test.LoadFile(String path)
at LCPDFR_Loader.Test.LoadAssembly()
at LCPDFR_Loader.Loader.Load()
at LCPDFR_Loader.Loader.Loader_Tick(Object sender, EventArgs e)
at GTA.Script.TryTick()
at GTA.Script.DoTick()
at GTA.ScriptThread.OnTick()