hlfhrtd

I also just recently found out that adding the "Microsoft.Expression.Drawing.dll" file from the LSPDFR download to the game directory fixes the problem. The RPH download does not have this file.

I ended up being able to open RPH by installing LSPDFR instead of basic RPH. I don't know why it wasn't opening. I guess some file in LSPDFR is allowing it to run. I don't play with LSPDFR so I turn it off in plugins but it's certainly a weird fix. I actually talked to some moderator about it on discord and all he said was "it's your system, but I'm not here to explain that." Lmao. Also, I tried many things before this, vanilla game with no mods, AV off, all that jazz. There's actually quite a lot of people with this exact same problem on the discord and the forums. Nobody has really said what is causing it yet.

then the problem is in the mods folder, remove the mods folder and try again

do this how i say in order no shortcuts or something
1.verify game files
2. open RPH while holding left shift then go to plugins and click load all plugins and then save and launch
3.then let it open then when it crashes or doesnt
4.after that reset your computer
5. open rph with admin mode
also if u have mods from https://www.gta5-mods.com/ it can crash ur game ive deleted those mods from that site and it worked.
 
if it doesnt help send a picture of your plugins folder in Grand Theft Auto V/plugins also plugins/LSPDFR

The problem was Scripthookvdotnet the whole time for me. Take it out it runs the LSR plugin, put it & it doesn't. 

Just re-installed everything in that order, no joy. Shows loading story mode at the bottom instead of loading los santos red, I can already tell when it's not going to work. I'm so confused but I give up, thanks for all the help. Just going to take it out.

Try to install only ScriptHookV (without trainer) ScriptHook.Net, RagePlugin Hook (without LSPDFR), LSR, Gameconfig, Packfile Limit Adjuster, and Heap Adjuster, if it will work, so it's 100% should be compability problem. I recommend doing it on a clean version of the game.

Tried this, don't believe it'll work but it's on you. Mines also detect win 10 and I'm on win 11. I believe it's an anti-virus but I'm not positive yet, many people having this same problem all of a sudden.