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Cyan posted this in another thread earlier today. Try renaming the agency file in the custom folder. 
 
You could also try removing the latest R* DLC from the dlclist.xml so those new police vehicles won't be able to spawn in at all. Unfortunately you would also lose access to the non police vehicles in that update too.

No not your mods folder, there should be folder named custom in the lspdfr/data folder by default. If not then just create it and place your edited version of agency.xml there. be sure to leave the unedited version in the data folder as a backup.
 
Grand Theft Auto V/lspdfr/data/custom 

Copy the agency.xml to the custom folder and make edits to that one. Any file in the custom folder will override the default file in the parent folder. You don't need to change those values, just delete those 4 lines entirely. The police1,2 & 3 values are already there above the lines you circled. 
 
edit: you don't need openiv to change these. just go straight to the lspdfr folder in your main GTA V directory. 
 
edit2: also note that those cars are listed throughout the agency.xml file in other places as they are assigned to different agencies. You'll need to edit each agency to make sure they don't spawn in other places like the sheriffs dept.

Yes, it is. Microsoft does not like the fact RPH is unsigned and when an update is pushed out, multiple people run it, and it flags as an anomaly to Windows Defender.