RagePluginHook "hooks" onto Grand Theft Auto V. It can be done at any stage of the application, people with Natural Visions Evolved know that you can't launch RPH to start your game, you have to load Grand Theft Auto V first, wait for the legal crap to pass, then launch RagePluginHook, in some cases you can wait until you're logged into the story mode, and then once in launch RagePluginHook, use F4 for console and type "reloadallplugins" (if you have multiple plugins) or just type "loadplugin LSPD First Response.dll"
Let me know if that works for you. Though if your problems persists and you haven't added very many things, I'd suggest reinstalling LSPDFR and make sure it's done correctly.