I'm sorry to hear that.. :/
I guess windows 10 is the real case then. Hope something gets done about it soon. Even though my crashing cleared and everything works fine now, I have to mention that if anyone else has other mods other than LSPDFR, too, they need to be installed correctly. I had LSPDFR crashing once in a while when it tried to generate a callout from a different mod. At first I thought it really is my Windows 10 messing with LSPDFR or RGH, but after I took a closer look at the error message in log file and then investigated all my plugins and did a fresh re-install, it works excellent now. It couldn't locate one file for custom callouts and that was making my LSPDFR crash.
Maybe it's helpful to mention that before all my steps which are mentioned above in the thread worked, I did re-install RGH and LSPDFR more than 3 times. Deleting any other .dll .asi or anything that belongs to mods was one thing I did too.
Lets just hope for a fix from devs soon!